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Sensitivity and Specificity of Transcranial Doppler Ultrasonography in the Detection of High-Grade Carotid Stenosis Neurol 43:1187-1191, Kelley,R.E.,et al, 1993 See this aricle in Pubmed Article Abstract We evaluated the ability of transcranial Doppler ultrasonography(TCD)of the middle cerebral artery to detect internal carotid artery luminal area stenosis of 70%or greater by comparing TCD with cerebral angiography in 79 subjects,including 22 with normal cerebral arteriograms and 57 with 30%to 100%internal carotid artery stenosis on at least one side.Of six TCD measurements assessed,the flow acceleration provided the greatest sensitivity(82%)and specificity(73%)in distinguishing 70%to 100%carotid stenosis from lesser degrees of stenosis.The overall accuracy of the flow acceleration was 78%,and the positive predictive value was 79%.A flow acceleration of 351.6%cm/sec or less was useful for detecting high-grade stenosis,but there was difficulty in distinguishing unilateral from bilateral high-grade stenosis.TCD measurement of the flow acceleration allows for fairly reliable detection of high-grade stenosis and can thus serve as a useful indirect component of a carotid noninvasive battery.

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(click to filter results - removes previous filter) carotid artery carotid artery disease carotid artery disease,noninvasive evaluation of carotid artery stenosis doppler doppler,transcranial

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